2-(Methoxycarbonyl)Phenylboronic Acid

2-(Methoxycarbonyl)Phenylboronic Acid - Names and Identifiers

Name	2-Methoxycarbonylphenylboronic acid
Synonyms	METHYL 2-BORONOBENZOATE 2-(Methoxycarbonyl)Phenylboron 2-Carbomethoxybenzeneboronicacid 2-Methoxycarbonylphenylboronic acid 2-METHOXYCARBONYLPHENYLBORONIC ACID 2-(Methoxycarbonyl)Phenylboronic Acid O-(METHOXYCARBONYL)PHENYLBORONIC ACID 2-(METHOXYCARBONYL)BENZENEBORONIC ACID Benzoic acid, 2-borono-, 1-methyl ester (9CI) 2-(Methoxycarbonyl)phenylboronic Acid (contains varying amounts of Anhydride)
CAS	374538-03-1
InChI	InChI=1/C8H9BO4/c1-13-8(10)6-4-2-3-5-7(6)9(11)12/h2-5,11-12H,1H3

2-(Methoxycarbonyl)Phenylboronic Acid - Physico-chemical Properties

Molecular Formula	C8H9BO4
Molar Mass	179.97
Density	1.25±0.1 g/cm3(Predicted)
Melting Point	90-96°C
Boling Point	359.0±44.0 °C(Predicted)
Flash Point	170.9°C
Vapor Presure	8.89E-06mmHg at 25°C
Appearance	Crystalline Powder
Color	White
BRN	8313459
pKa	8.19±0.58(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.532
MDL	MFCD02179452
Physical and Chemical Properties	Melting point 90-96°C BRN 8313459

2-(Methoxycarbonyl)Phenylboronic Acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
WGK Germany	3
TSCA	No
HS Code	29163990
Hazard Class	IRRITANT

2-(Methoxycarbonyl)Phenylboronic Acid - Introduction

Acid is an organic compound with the chemical formula C9H9BO4. It has the morphology of a white crystalline powder.

Nature:
-Melting point: about 150-155°C.
-Solubility: Soluble in water, alcohols, ethers, ether alkanes, dimethyl sulfoxide and other polar solvents. Slightly soluble in non-polar solvents.
-Stability: relatively stable under normal conditions, but avoid contact with strong oxidants, strong acids and strong bases to avoid reactions.

Use:
-or acid is commonly used as a reagent and intermediate in organic synthesis.
-It can be used to synthesize compounds containing phenylboronic acid groups, such as drug synthesis, Suzuki coupling reaction in organic synthesis, etc. In organic synthesis, it often reacts with oxidants, nucleophiles and metal ligands to generate target compounds with useful biological activity.

Preparation Method:
There are many ways to prepare acid. A common method is to use hydroxypropyl acetate as raw material, through the action of phenylboronic acid, alkali and chemical reducing agent, through esterification, alcoholysis and hydrolysis steps.

Safety Information:
The acid has no obvious toxicity under general conditions, but the following safety precautions should be paid attention:
-Avoid contact and inhalation of powder or solution. In case of contact with eyes or skin, rinse immediately with plenty of water and seek medical help.
-Pay attention to avoid touching the skin directly during operation. Appropriate protective gloves and eye protection are recommended for laboratory operations.
-should be stored in a dry, well-ventilated place, and away from fire and oxidizing agents.

Please note that the above information is for reference only. For specific use, it is necessary to operate carefully in combination with different situations and experimental conditions, and refer to the detailed safety data sheet of the relevant chemical.

Last Update：2024-04-09 15:17:57